Activity record

PGDB_A015982

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

IC50 = 31 uM

TargetGSPT1
Cell lineHEK293
Time6 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002153
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007936
Compound IDPGDB_C007936
Compound5;5;5;Example 5
Source record IDPGDB_C007936
InChIKeyNQQLZILJZVNOKX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002153
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDWO2025043225
Compound location

5;5;5;Example 5

5;5;5;Example 5 enlarged structure5;5;5;Example 5 location on patent page 22
Activity table
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