Activity record

PGDB_A016010

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

DC50 = 950 nM

TargetIKZF1
Time20 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001718
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010126
Compound IDPGDB_C010126
Compound2
Source record IDPGDB_C010126
InChIKeyKLWWIJBBBDWGRY-VNHLFDKOSA-N

Assay context

Assay IDPGDB_AS001718
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time20 h
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

2

2 enlarged structure2 location on patent page 85
Activity table
Page 106 · table single