Activity record

PGDB_A016014

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Kd = 0.23 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutKd / binding
Assay IDPGDB_AS000368
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008014
Compound IDPGDB_C008014
Compound110;110;110
Source record IDPGDB_C008014
InChIKeyFPHAWDUBAMOXJL-ZVDHGWRTSA-N

Assay context

Assay IDPGDB_AS000368
Assay familybinding
Assay systembiochemical
ReadoutKd
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

110;110;110

110;110;110 enlarged structure110;110;110 location on patent page 27
Activity table
Page 527 · table start
Page 528 · table end