Activity record

PGDB_A016021

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 1-1.5 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000323
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000753
Compound IDPGDB_C000753
CompoundGT-04377
Source record IDPGDB_C000753
InChIKeyTVINBOZRKBOTGT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000323
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDCN120548310A
Compound location

GT-04377

GT-04377 enlarged structureGT-04377 location on patent page 23
Activity table
Page 146 · table single