Assay

PGDB_AS000323

System: biochemicalTarget: CRBN
Assay context summary

Assay context

27 activity records
Assay familybiochemical
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
OrganismHomo sapiens
TechnologyHTRF
Activity compounds and values

Activity records

27 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C000778
IC50-=1-1.5uM-—CRBNCRBN-CN120548310APGDB_A007424PGDB_C000778PGDB_AS000323View
2D structure for PGDB_C000782
IC50-=1.5-1.9uM-—CRBNCRBN-CN120548310APGDB_A008015PGDB_C000782PGDB_AS000323View
2D structure for PGDB_C000740
IC50-<=0.1uM-—CRBNCRBN-CN120548310APGDB_A012527PGDB_C000740PGDB_AS000323View
2D structure for PGDB_C000753
IC50-=1-1.5uM-—CRBNCRBN-CN120548310APGDB_A016021PGDB_C000753PGDB_AS000323View
2D structure for PGDB_C000759
IC50-=1-1.5uM-—CRBNCRBN-CN120548310APGDB_A019646PGDB_C000759PGDB_AS000323View
2D structure for PGDB_C000765
IC50-=1.5-1.9uM-—CRBNCRBN-CN120548310APGDB_A022449PGDB_C000765PGDB_AS000323View
2D structure for PGDB_C000752
IC50-=1-1.5uM-—CRBNCRBN-CN120548310APGDB_A022690PGDB_C000752PGDB_AS000323View
2D structure for PGDB_C000754
IC50-=1.5-1.9uM-—CRBNCRBN-CN120548310APGDB_A025285PGDB_C000754PGDB_AS000323View
2D structure for PGDB_C000779
IC50-=0.5-1uM-—CRBNCRBN-CN120548310APGDB_A025900PGDB_C000779PGDB_AS000323View
2D structure for PGDB_C000769
IC50-=1-1.5uM-—CRBNCRBN-CN120548310APGDB_A031041PGDB_C000769PGDB_AS000323View
2D structure for PGDB_C000776
IC50-=0.5-1uM-—CRBNCRBN-CN120548310APGDB_A031342PGDB_C000776PGDB_AS000323View
2D structure for PGDB_C000770
IC50-=0.5-1uM-—CRBNCRBN-CN120548310APGDB_A033586PGDB_C000770PGDB_AS000323View
2D structure for PGDB_C000760
IC50-=0.5-1uM-—CRBNCRBN-CN120548310APGDB_A041929PGDB_C000760PGDB_AS000323View
2D structure for PGDB_C000764
IC50-=0.5-1uM-—CRBNCRBN-CN120548310APGDB_A044292PGDB_C000764PGDB_AS000323View
2D structure for PGDB_C000741
IC50-<=0.1uM-—CRBNCRBN-CN120548310APGDB_A044789PGDB_C000741PGDB_AS000323View
2D structure for PGDB_C000757
IC50-=0.5-1uM-—CRBNCRBN-CN120548310APGDB_A048349PGDB_C000757PGDB_AS000323View
2D structure for PGDB_C000771
IC50-=1-1.5uM-—CRBNCRBN-CN120548310APGDB_A051170PGDB_C000771PGDB_AS000323View
2D structure for PGDB_C000775
IC50-<=0.1uM-—CRBNCRBN-CN120548310APGDB_A051668PGDB_C000775PGDB_AS000323View
2D structure for PGDB_C000756
IC50-<=0.1uM-—CRBNCRBN-CN120548310APGDB_A055418PGDB_C000756PGDB_AS000323View
2D structure for PGDB_C000762
IC50-<=0.1uM-—CRBNCRBN-CN120548310APGDB_A056171PGDB_C000762PGDB_AS000323View
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