Activity record

PGDB_A016332

Assay: % DegradationTarget: IKZF3QC: standardized
Activity overview

DC50 > 10000 nM

TargetIKZF3
Cell lineJurkat
Time72 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS001077
PatentCN121646585A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007381
Compound IDPGDB_C007381
CompoundCOMPARATIVE COMPOUND A
Source record IDPGDB_C007381
InChIKeyOHSPSWUQMQUVMW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001077
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time72 h
TargetIKZF3
E3Not specified
Cell lineJurkat

Source evidence

Patent IDCN121646585A
Compound location

COMPARATIVE COMPOUND A

COMPARATIVE COMPOUND A enlarged structureCOMPARATIVE COMPOUND A location on patent page 71
Activity table
Page 73 · table start
Page 74 · table end