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SIMM · NJU
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SIMM · NJU
Activity record
PGDB_A016708
Assay: % Degradation
Target: GSPT1
QC: standardized
Activity overview
IC50 = 6 uM
Target
GSPT1
E3 ligase
CRBN
Cell line
HEK293
Time
6 h
Assay / Readout
luminescence / IC50
Assay ID
PGDB_AS000357
Patent
WO2025043225
QC status
standardized
Evidence details
Compound, assay context, and source
Compound
Compound ID
PGDB_C008063
Compound
133;133;133
Source record ID
PGDB_C008063
InChIKey
AHQZYRCIBWFNPO-OSQZJCSBSA-N
Assay context
Assay ID
PGDB_AS000357
Assay family
% Degradation
Assay system
cell_based
Readout
IC50
Technology
luminescence
Treatment time
6 h
Target
GSPT1
E3
CRBN
Cell line
HEK293
Source evidence
Patent ID
WO2025043225
Compound location
133;133;133
Activity table