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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A016848

Assay: % DegradationTarget: IKZF2QC: standardized

Activity overview

Dmax >= 75 %

TargetIKZF2

Concentration1 uM

Time24 h

Assay / ReadoutWestern_blot / Dmax

Assay IDPGDB_AS001154

PatentWO2025067466A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C005450

Compound4;4;实施例 4

Source record IDPGDB_C005450

InChIKeyURUJMKOPNNHTOJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001154

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

TechnologyWestern_blot

Concentration1 uM

Treatment time24 h

Detection targetprotein_degradation

TargetIKZF2

E3Not specified

OrganismHomo sapiens

Source evidence

Patent IDWO2025067466A1

Compound location

4;4;实施例 4

4;4;实施例 4 enlarged structure

4;4;实施例 4 location on patent page 16

Activity table

Page 65 · table start

Page 66 · table middle

Page 67 · table middle

Page 68 · table middle

Page 69 · table middle

Page 70 · table middle

Page 71 · table middle

Page 72 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU