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SIMM · NJU
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SIMM · NJU
Patent
WO2025067466A1
14 compounds
14 activity records
1 assays
Patent summary
Publication number
WO2025067466A1
Assignee
Hangzhou Polymed Biopharmaceuticals
Title
Heterocyclic compound, and composition and use thereof
Family ID
95204383
Family members
1
Family patent IDs
WO2025067466A1
Filing year
2024
Publication date
2025-04-03
Jurisdiction
WO
Compounds
14
Activity records
14
Assays
1
Activity compounds and values
Activity records
14 records
Structure
Metric
Control
Relation
Value
Unit
Concentration
Time
Target
E3
Cell line
Record ID
Compound
Assay
Details
Dmax
-
=
50-75
%
1 uM
24 h
IKZF2
-
-
PGDB_A010395
PGDB_C005457
PGDB_AS001154
View
Dmax
-
<=
50
%
1 uM
24 h
IKZF2
-
-
PGDB_A012593
PGDB_C005454
PGDB_AS001154
View
Dmax
-
>=
75
%
1 uM
24 h
IKZF2
-
-
PGDB_A016848
PGDB_C005450
PGDB_AS001154
View
Dmax
-
<=
50
%
1 uM
24 h
IKZF2
-
-
PGDB_A020214
PGDB_C005448
PGDB_AS001154
View
Dmax
-
=
50-75
%
1 uM
24 h
IKZF2
-
-
PGDB_A026721
PGDB_C005461
PGDB_AS001154
View
Dmax
-
=
50-75
%
1 uM
24 h
IKZF2
-
-
PGDB_A031015
PGDB_C005460
PGDB_AS001154
View
Dmax
-
>=
75
%
1 uM
24 h
IKZF2
-
-
PGDB_A039004
PGDB_C005452
PGDB_AS001154
View
Dmax
-
=
50-75
%
1 uM
24 h
IKZF2
-
-
PGDB_A043953
PGDB_C005449
PGDB_AS001154
View
Dmax
-
<=
50
%
1 uM
24 h
IKZF2
-
-
PGDB_A044914
PGDB_C005455
PGDB_AS001154
View
Dmax
-
<=
50
%
1 uM
24 h
IKZF2
-
-
PGDB_A050427
PGDB_C005459
PGDB_AS001154
View
Dmax
-
=
50-75
%
1 uM
24 h
IKZF2
-
-
PGDB_A062148
PGDB_C005458
PGDB_AS001154
View
Dmax
-
=
50-75
%
1 uM
24 h
IKZF2
-
-
PGDB_A062846
PGDB_C005456
PGDB_AS001154
View
Dmax
-
<=
50
%
1 uM
24 h
IKZF2
-
-
PGDB_A070317
PGDB_C005451
PGDB_AS001154
View
Dmax
-
=
50-75
%
1 uM
24 h
IKZF2
-
-
PGDB_A075148
PGDB_C005453
PGDB_AS001154
View