Assay

PGDB_AS001154

System: cell_based
Assay context summary

Assay context

14 activity records
Assay family% Degradation
Systemcell_based
ReadoutDmax
E3Not specified
OrganismHomo sapiens
TechnologyWestern_blot
Detection targetprotein_degradation
Activity compounds and values

Activity records

14 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C005457
Dmax-=50-75%1 uM24 hIKZF2--WO2025067466A1PGDB_A010395PGDB_C005457PGDB_AS001154View
2D structure for PGDB_C005454
Dmax-<=50%1 uM24 hIKZF2--WO2025067466A1PGDB_A012593PGDB_C005454PGDB_AS001154View
2D structure for PGDB_C005450
Dmax->=75%1 uM24 hIKZF2--WO2025067466A1PGDB_A016848PGDB_C005450PGDB_AS001154View
2D structure for PGDB_C005448
Dmax-<=50%1 uM24 hIKZF2--WO2025067466A1PGDB_A020214PGDB_C005448PGDB_AS001154View
2D structure for PGDB_C005461
Dmax-=50-75%1 uM24 hIKZF2--WO2025067466A1PGDB_A026721PGDB_C005461PGDB_AS001154View
2D structure for PGDB_C005460
Dmax-=50-75%1 uM24 hIKZF2--WO2025067466A1PGDB_A031015PGDB_C005460PGDB_AS001154View
2D structure for PGDB_C005452
Dmax->=75%1 uM24 hIKZF2--WO2025067466A1PGDB_A039004PGDB_C005452PGDB_AS001154View
2D structure for PGDB_C005449
Dmax-=50-75%1 uM24 hIKZF2--WO2025067466A1PGDB_A043953PGDB_C005449PGDB_AS001154View
2D structure for PGDB_C005455
Dmax-<=50%1 uM24 hIKZF2--WO2025067466A1PGDB_A044914PGDB_C005455PGDB_AS001154View
2D structure for PGDB_C005459
Dmax-<=50%1 uM24 hIKZF2--WO2025067466A1PGDB_A050427PGDB_C005459PGDB_AS001154View
2D structure for PGDB_C005458
Dmax-=50-75%1 uM24 hIKZF2--WO2025067466A1PGDB_A062148PGDB_C005458PGDB_AS001154View
2D structure for PGDB_C005456
Dmax-=50-75%1 uM24 hIKZF2--WO2025067466A1PGDB_A062846PGDB_C005456PGDB_AS001154View
2D structure for PGDB_C005451
Dmax-<=50%1 uM24 hIKZF2--WO2025067466A1PGDB_A070317PGDB_C005451PGDB_AS001154View
2D structure for PGDB_C005453
Dmax-=50-75%1 uM24 hIKZF2--WO2025067466A1PGDB_A075148PGDB_C005453PGDB_AS001154View
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