Activity record

PGDB_A016875

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 3.7 nM

TargetGSPT1
Cell lineHNT-34
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000001
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005350
Compound IDPGDB_C005350
Compound5-46;5-46;5-46;5-46
Source record IDPGDB_C005350
InChIKeyGGUXMQNOHQLANC-HMTLIYDFSA-N

Assay context

Assay IDPGDB_AS000001
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineHNT-34

Source evidence

Patent IDWO2023078410A1
Compound location

5-46;5-46;5-46;5-46

5-46;5-46;5-46;5-46 enlarged structure5-46;5-46;5-46;5-46 location on patent page 25
Activity table
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