PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

23 activity records

Assay familyviability

Systemcell_based

ReadoutIC50

E3Not specified

Cell lineHNT-34

Technologyluminescence

Detection targetcell_proliferation

Activity compounds and values

Activity records

23 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
IC50	-	=	6.2	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A014569	PGDB_C005308	PGDB_AS000001	View
IC50	-	=	26.9	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A014587	PGDB_C005300	PGDB_AS000001	View
IC50	-	=	3.7	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A016875	PGDB_C005350	PGDB_AS000001	View
IC50	-	=	3.8	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A023432	PGDB_C005309	PGDB_AS000001	View
IC50	-	=	32.7	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A025216	PGDB_C005340	PGDB_AS000001	View
IC50	-	=	6.6	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A027000	PGDB_C005305	PGDB_AS000001	View
IC50	-	=	3.2	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A027590	PGDB_C005303	PGDB_AS000001	View
IC50	-	=	7.5	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A031614	PGDB_C005326	PGDB_AS000001	View
IC50	-	=	3.2	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A033979	PGDB_C005329	PGDB_AS000001	View
IC50	-	=	21.3	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A034275	PGDB_C005355	PGDB_AS000001	View
IC50	-	=	7.8	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A035161	PGDB_C005331	PGDB_AS000001	View
IC50	-	=	6.6	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A035567	PGDB_C005333	PGDB_AS000001	View
IC50	-	=	3.2	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A040114	PGDB_C005327	PGDB_AS000001	View
IC50	-	=	11.3	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A041127	PGDB_C005306	PGDB_AS000001	View
IC50	-	=	7.4	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A041601	PGDB_C005353	PGDB_AS000001	View
IC50	-	=	36.9	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A043170	PGDB_C005337	PGDB_AS000001	View
IC50	-	=	6.9	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A044820	PGDB_C005354	PGDB_AS000001	View
IC50	-	=	6.5	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A046286	PGDB_C005304	PGDB_AS000001	View
IC50	-	=	8.7	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A049831	PGDB_C005330	PGDB_AS000001	View
IC50	-	=	18	nM	-	—	GSPT1	-	HNT-34	WO2023078410A1	PGDB_A050341	PGDB_C005301	PGDB_AS000001	View

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