Activity record

PGDB_A016906

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

DC50 > 10000 nM

TargetIKZF3
Cell lineJurkat
Time72 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS000744
PatentUS20250129061A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007373
Compound IDPGDB_C007373
CompoundComparative Compound B
Source record IDPGDB_C007373
InChIKeyVACYFJWFXFNBTI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000744
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time72 h
TargetIKZF3
E3Not specified
Cell lineJurkat

Source evidence

Patent IDUS20250129061A1
Compound location

Comparative Compound B

Comparative Compound B enlarged structureComparative Compound B location on patent page 76
Activity table
Page 79 · table single