Search Browse Statistics Contact Help

·

SIMM · NJU

Loading activity

Loading detail record from the SQLite release...

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

Search Browse Statistics Contact Help

·

SIMM · NJU

Activity record

PGDB_A017131

Assay: % DegradationQC: ambiguous

Activity overview

Dmax = 60 %

Cell lineNCI-H929

ConcentrationConcentration series: 1600 nM, 400 nM, 100 nM, 25 nM, 6.25 nM, 1.56 nM, 0.39 nM, 0.1 nM

Time24 h

Assay / ReadoutWestern_blot / Dmax

Assay IDPGDB_AS000327

PatentEP4685141A1

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C025619

Compound实施例 25

Source record IDPGDB_C025619

InChIKeyHDAAFKBDUXDETD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000327

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

TechnologyWestern_blot

ConcentrationConcentration series: 1600 nM, 400 nM, 100 nM, 25 nM, 6.25 nM, 1.56 nM, 0.39 nM, 0.1 nM

Treatment time24 h

Detection targetprotein_degradation

E3Not specified

Cell lineNCI-H929

OrganismHomo sapiens

Source evidence

Patent IDEP4685141A1

Compound location

实施例 25

实施例 25 enlarged structure

实施例 25 location on patent page 50

Activity table

Page 67 · table start

Page 68 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU