Activity record

PGDB_A017133

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

IC50 = 31 uM

TargetGSPT1
Cell lineHEK293
Time18 h
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001575
PatentWO2025043225
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008031
Compound IDPGDB_C008031
Compound50;50;50
Source record IDPGDB_C008031
InChIKeySJQOIFZPICCOMZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001575
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time18 h
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

50;50;50

50;50;50 enlarged structure50;50;50 location on patent page 39
Activity table
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