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Compound
PGDB_C008031
7 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(CNC(=O)OC4CC(c5ccc(C(F)(F)F)cc5)C4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 31 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A013328 | PGDB_C008031 | PGDB_AS002240 | View |
| IC50 | - | = | 0.044 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A013965 | PGDB_C008031 | PGDB_AS000958 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A015741 | PGDB_C008031 | PGDB_AS002508 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A017133 | PGDB_C008031 | PGDB_AS001575 | View |
| Dmax | - | = | 25 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A022359 | PGDB_C008031 | PGDB_AS000735 | View |
| IC50 | - | = | 0.99 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A023516 | PGDB_C008031 | PGDB_AS002405 | View |
| IC50 | - | = | 0.16 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A051999 | PGDB_C008031 | PGDB_AS000366 | View |