Activity record

PGDB_A017313

Assay: biochemicalTarget: KRASQC: ambiguous
Activity overview

IC50 = 10-100 nM

TargetKRAS
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000791
PatentWO2025214350A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011614
Compound IDPGDB_C011614
CompoundExample 33
Source record IDPGDB_C011614
InChIKeyLSALNIBFVVRWEB-PQXSFQNBSA-N

Assay context

Assay IDPGDB_AS000791
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetRAF1 | SOS1
E3Not specified

Source evidence

Patent IDWO2025214350A1
Compound location

Example 33

Example 33 enlarged structureExample 33 location on patent page 59
Activity table
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