Assay

PGDB_AS000791

System: biochemicalTarget: RAF1 | SOS1
Assay context summary

Assay context

41 activity records
Assay familybiochemical
Systembiochemical
ReadoutIC50
TargetRAF1 | SOS1
E3Not specified
TechnologyHTRF
Activity compounds and values

Activity records

41 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C011589
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A016647PGDB_C011589PGDB_AS000791View
2D structure for PGDB_C011617
IC50-=10-100nM-—KRAS--WO2025214350A1PGDB_A016806PGDB_C011617PGDB_AS000791View
2D structure for PGDB_C011614
IC50-=10-100nM-—KRAS--WO2025214350A1PGDB_A017313PGDB_C011614PGDB_AS000791View
2D structure for PGDB_C011619
IC50-=100-1000nM-—KRAS--WO2025214350A1PGDB_A022996PGDB_C011619PGDB_AS000791View
2D structure for PGDB_C011625
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A023654PGDB_C011625PGDB_AS000791View
2D structure for PGDB_C011588
IC50-=10-100nM-—KRAS--WO2025214350A1PGDB_A026494PGDB_C011588PGDB_AS000791View
2D structure for PGDB_C011606
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A028789PGDB_C011606PGDB_AS000791View
2D structure for PGDB_C011598
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A029021PGDB_C011598PGDB_AS000791View
2D structure for PGDB_C011592
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A030014PGDB_C011592PGDB_AS000791View
2D structure for PGDB_C011595
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A030762PGDB_C011595PGDB_AS000791View
2D structure for PGDB_C011600
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A032460PGDB_C011600PGDB_AS000791View
2D structure for PGDB_C011613
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A034347PGDB_C011613PGDB_AS000791View
2D structure for PGDB_C011602
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A035604PGDB_C011602PGDB_AS000791View
2D structure for PGDB_C011587
IC50-=10-100nM-—KRAS--WO2025214350A1PGDB_A036278PGDB_C011587PGDB_AS000791View
2D structure for PGDB_C011607
IC50-=10-100nM-—KRAS--WO2025214350A1PGDB_A037688PGDB_C011607PGDB_AS000791View
2D structure for PGDB_C011604
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A038203PGDB_C011604PGDB_AS000791View
2D structure for PGDB_C011590
IC50-=10-100nM-—KRAS--WO2025214350A1PGDB_A038255PGDB_C011590PGDB_AS000791View
2D structure for PGDB_C011627
IC50-=1-10nM-—KRAS--WO2025214350A1PGDB_A040320PGDB_C011627PGDB_AS000791View
2D structure for PGDB_C011622
IC50-=100-1000nM-—KRAS--WO2025214350A1PGDB_A040967PGDB_C011622PGDB_AS000791View
2D structure for PGDB_C011623
IC50-=10-100nM-—KRAS--WO2025214350A1PGDB_A041005PGDB_C011623PGDB_AS000791View
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