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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A017320

Assay: % DegradationTarget: GSPT1QC: standardized

Activity overview

degradation = 99 %

TargetGSPT1

Cell lineJeKo-1

Concentration100 nM

Time24 h

Assay / ReadoutWestern_blot / % Degradation

Assay IDPGDB_AS002119

PatentWO2023078410A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C005358

Compound5-93;5-93;5-93;5-93;5-93

Source record IDPGDB_C005358

InChIKeyANIODNFQHMQYNI-UXMRNZNESA-N

Assay context

Assay IDPGDB_AS002119

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

TechnologyWestern_blot

Concentration100 nM

Treatment time24 h

Detection targetprotein_degradation

TargetGSPT1

E3Not specified

Cell lineJeKo-1

Source evidence

Patent IDWO2023078410A1

Compound location

5-93;5-93;5-93;5-93;5-93

5-93;5-93;5-93;5-93;5-93 enlarged structure

5-93;5-93;5-93;5-93;5-93 location on patent page 11

Activity table

Page 91 · table start

Page 92 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

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0 countries/regions

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SIMM · NJU