Activity record

PGDB_A017557

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Kd = 0.26 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutKd / binding
Assay IDPGDB_AS000522
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008072
Compound IDPGDB_C008072
Compound142;142;142
Source record IDPGDB_C008072
InChIKeyAHNJEHXBEDATDC-FKEKPDDDSA-N

Assay context

Assay IDPGDB_AS000522
Assay familybinding
Assay systembiochemical
ReadoutKd
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

142;142;142

142;142;142 enlarged structure142;142;142 location on patent page 43
Activity table
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Page 530 · table middle
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Page 532 · table end