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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A017687

Assay: viabilityTarget: GSPT1QC: ambiguous

Activity overview

IC50 = 10.08 nM

TargetGSPT1

Cell lineSK-BR-3

Time3 d

Assay / Readoutluminescence / IC50

Assay IDPGDB_AS000582

PatentWO2025252247A1

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C005478

Compound实施例 28;实施例 28

Source record IDPGDB_C005478

InChIKeyLWYXIFGYLYJMMN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000582

Assay familyviability

Assay systemcell_based

ReadoutIC50

Technologyluminescence

Treatment time3 d

Detection target% Cell viability

TargetGSPT1

E3Not specified

Cell lineSK-BR-3

OrganismHomo sapiens

Source evidence

Patent IDWO2025252247A1

Compound location

实施例 28;实施例 28

实施例 28;实施例 28 enlarged structure

实施例 28;实施例 28 location on patent page 83

Activity table

Page 157 · table start

Page 158 · table middle

Page 159 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU