Activity record

PGDB_A018327

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 70-80 %

TargetCRBN
E3 ligaseCRBN
Concentration2 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS001462
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000802
Compound IDPGDB_C000802
CompoundGT-09347
Source record IDPGDB_C000802
InChIKeyVQRKOANRURSPQE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001462
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration2 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN

Source evidence

Patent IDCN120548310A
Compound location

GT-09347

GT-09347 enlarged structureGT-09347 location on patent page 25
Activity table
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