Activity record

PGDB_A018378

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

DC50 = 113 nM

TargetIKZF1
Time24 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS000255
PatentUS20250129061A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007372
Compound IDPGDB_C007372
CompoundComparative Compound A
Source record IDPGDB_C007372
InChIKeyCNNZMWHBTVDISB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000255
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time24 h
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDUS20250129061A1
Compound location

Comparative Compound A

Comparative Compound A enlarged structureComparative Compound A location on patent page 74
Activity table
Page 85 · table single