Activity record

PGDB_A018805

Assay: viabilityTarget: BRAFQC: standardized
Activity overview

IC50 > 1000 nM

TargetBRAF
Cell lineA375
Time5-day treatment
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS001949
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011604
Compound IDPGDB_C011604
CompoundExample 17;Example 17
Source record IDPGDB_C011604
InChIKeyYNNLIRCRYKYBPT-XXGQOMGMSA-N

Assay context

Assay IDPGDB_AS001949
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5-day treatment
Detection target% Cell viability
TargetBRAF
E3Not specified
Cell lineA375
OrganismHomo sapiens

Source evidence

Patent IDWO2025214350A1
Compound location

Example 17;Example 17

Example 17;Example 17 enlarged structureExample 17;Example 17 location on patent page 58
Activity table
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