Activity record

PGDB_A018920

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

Dmax = 74 %

TargetIKZF1
ConcentrationConcentration context: titrated doses of compound
Time24 h
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS001411
PatentUS20250129061A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007372
Compound IDPGDB_C007372
CompoundComparative Compound A
Source record IDPGDB_C007372
InChIKeyCNNZMWHBTVDISB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001411
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
ConcentrationConcentration context: titrated doses of compound
Treatment time24 h
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDUS20250129061A1
Compound location

Comparative Compound A

Comparative Compound A enlarged structureComparative Compound A location on patent page 74
Activity table
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