Activity record

PGDB_A018937

Assay: cellular_functionTarget: BRD4QC: ambiguous
Activity overview

EC50 = 8.29 uM

TargetBRD4
E3 ligaseCRBN
Cell lineFlip-InTM293
Time5 h
Assay / Readoutflow_cytometry / EC50
Assay IDPGDB_AS001859
PatentUS12110292B2
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009030
Compound IDPGDB_C009030
Compound50
Source record IDPGDB_C009030
InChIKeyOLKNHYAREPHHNP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001859
Assay familycellular_function
Assay systemcell_based
ReadoutEC50
Technologyflow_cytometry
Treatment time5 h
TargetBRD4
E3CRBN
Cell lineFlip-InTM293
Organismmammalian

Source evidence

Patent IDUS12110292B2
Compound location

50

50 enlarged structure50 location on patent page 90
Activity table
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