PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

32 activity records

Assay familycellular_function

Systemcell_based

ReadoutEC50

TargetBRD4

E3CRBN

Cell lineFlip-InTM293

Organismmammalian

Technologyflow_cytometry

Activity compounds and values

Activity records

32 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
EC50	-	=	0.742	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A010131	PGDB_C009022	PGDB_AS001859	View
EC50	-	=	8.138	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A017047	PGDB_C009013	PGDB_AS001859	View
EC50	-	=	8.146	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A017683	PGDB_C009014	PGDB_AS001859	View
EC50	-	=	3.63	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A017721	PGDB_C009005	PGDB_AS001859	View
EC50	-	=	8.29	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A018937	PGDB_C009030	PGDB_AS001859	View
EC50	-	=	0.665	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A020231	PGDB_C009033	PGDB_AS001859	View
EC50	-	=	0.66	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A021281	PGDB_C009008	PGDB_AS001859	View
EC50	-	=	12.45	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A022657	PGDB_C009028	PGDB_AS001859	View
EC50	-	=	1.347	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A022710	PGDB_C009009	PGDB_AS001859	View
EC50	-	=	1.246	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A026544	PGDB_C009011	PGDB_AS001859	View
EC50	-	=	2.24	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A028469	PGDB_C009019	PGDB_AS001859	View
EC50	-	=	1.264	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A028835	PGDB_C009006	PGDB_AS001859	View
EC50	-	=	0.67	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A031001	PGDB_C009010	PGDB_AS001859	View
EC50	-	=	8.66	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A034365	PGDB_C009015	PGDB_AS001859	View
EC50	-	=	12.42	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A037691	PGDB_C009029	PGDB_AS001859	View
EC50	-	=	1.86	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A042661	PGDB_C009018	PGDB_AS001859	View
EC50	-	=	47.93	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A045381	PGDB_C008989	PGDB_AS001859	View
EC50	-	=	27.07	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A048627	PGDB_C009027	PGDB_AS001859	View
EC50	-	=	4.164	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A049247	PGDB_C009016	PGDB_AS001859	View
EC50	-	=	0.82	uM	-	—	BRD4	CRBN	Flip-InTM293	US12110292B2	PGDB_A053783	PGDB_C019024	PGDB_AS001859	View

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