Activity record

PGDB_A019011

Assay: biochemicalQC: ambiguous
Activity overview

selectivity_index = 11.5 fold

Time60 min
ControlCDK7 / CDK12
Assay / ReadoutFold change / biochemical
Assay IDPGDB_AS002236
PatentCN114929708B
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006568
Compound IDPGDB_C006568
CompoundH-APPAMP-001;H-APPAMP-001
Source record IDPGDB_C006568
InChIKeyXIKREHXNLXFBJK-XLIONFOSSA-N

Assay context

Assay IDPGDB_AS002236
Assay familybiochemical
Assay systembiochemical
ReadoutFold change
Treatment time60 min
TargetCDK12 | CDK7
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN114929708B
Compound location

H-APPAMP-001;H-APPAMP-001

H-APPAMP-001;H-APPAMP-001 enlarged structureH-APPAMP-001;H-APPAMP-001 location on patent page 36
Activity table
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