Assay

PGDB_AS002236

System: biochemicalTarget: CDK12 | CDK7
Assay context summary

Assay context

48 activity records
Assay familybiochemical
Systembiochemical
ReadoutFold change
TargetCDK12 | CDK7
E3Not specified
OrganismHomo sapiens
Activity compounds and values

Activity records

48 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C006571
Selectivity indexCDK7 / CDK12=5.9fold-—---CN114929708BPGDB_A009464PGDB_C006571PGDB_AS002236View
2D structure for PGDB_C006604
Selectivity indexCDK7 / CDK12=3.1fold-—---CN114929708BPGDB_A009806PGDB_C006604PGDB_AS002236View
2D structure for PGDB_C006606
Selectivity indexCDK7 / CDK12=38.1fold-—---CN114929708BPGDB_A012206PGDB_C006606PGDB_AS002236View
2D structure for PGDB_C006590
Selectivity indexCDK7 / CDK12=0.1fold-—---CN114929708BPGDB_A013684PGDB_C006590PGDB_AS002236View
2D structure for PGDB_C006579
Selectivity indexCDK7 / CDK12=8.2fold-—---CN114929708BPGDB_A017519PGDB_C006579PGDB_AS002236View
2D structure for PGDB_C006576
Selectivity indexCDK7 / CDK12=3.2fold-—---CN114929708BPGDB_A018719PGDB_C006576PGDB_AS002236View
2D structure for PGDB_C006608
Selectivity indexCDK7 / CDK12=14.1fold-—---CN114929708BPGDB_A018720PGDB_C006608PGDB_AS002236View
2D structure for PGDB_C006598
Selectivity indexCDK7 / CDK12=38.3fold-—---CN114929708BPGDB_A018855PGDB_C006598PGDB_AS002236View
2D structure for PGDB_C006568
Selectivity indexCDK7 / CDK12=11.5fold-—---CN114929708BPGDB_A019011PGDB_C006568PGDB_AS002236View
2D structure for PGDB_C006567
Selectivity indexCDK7 / CDK12=0.018fold-—---CN114929708BPGDB_A019298PGDB_C006567PGDB_AS002236View
2D structure for PGDB_C006588
Selectivity indexCDK7 / CDK12=0.2fold-—---CN114929708BPGDB_A021158PGDB_C006588PGDB_AS002236View
2D structure for PGDB_C006581
Selectivity indexCDK7 / CDK12=0.3fold-—---CN114929708BPGDB_A023594PGDB_C006581PGDB_AS002236View
2D structure for PGDB_C006589
Selectivity indexCDK7 / CDK12=3.8fold-—---CN114929708BPGDB_A024691PGDB_C006589PGDB_AS002236View
2D structure for PGDB_C006611
Selectivity indexCDK7 / CDK12=6.7fold-—---CN114929708BPGDB_A026266PGDB_C006611PGDB_AS002236View
2D structure for PGDB_C006587
Selectivity indexCDK7 / CDK12=0.2fold-—---CN114929708BPGDB_A027553PGDB_C006587PGDB_AS002236View
2D structure for PGDB_C006582
Selectivity indexCDK7 / CDK12=0.01fold-—---CN114929708BPGDB_A028683PGDB_C006582PGDB_AS002236View
2D structure for PGDB_C006580
Selectivity indexCDK7 / CDK12=3.2fold-—---CN114929708BPGDB_A030086PGDB_C006580PGDB_AS002236View
2D structure for PGDB_C006610
Selectivity indexCDK7 / CDK12=23fold-—---CN114929708BPGDB_A030194PGDB_C006610PGDB_AS002236View
2D structure for PGDB_C006605
Selectivity indexCDK7 / CDK12=7.6fold-—---CN114929708BPGDB_A031393PGDB_C006605PGDB_AS002236View
2D structure for PGDB_C006592
Selectivity indexCDK7 / CDK12=9.3fold-—---CN114929708BPGDB_A034221PGDB_C006592PGDB_AS002236View
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