Activity record

PGDB_A019376

Assay: % DegradationTarget: IKZF3QC: standardized
Activity overview

Dmax = 2 %

TargetIKZF3
ConcentrationConcentration context: titrated doses
Time24 h
Assay / Readoutflow_cytometry / Dmax
Assay IDPGDB_AS001615
PatentCN121646585A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007382
Compound IDPGDB_C007382
CompoundCOMPARATIVE COMPOUND B
Source record IDPGDB_C007382
InChIKeyUZLMRMVUVTXJJP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001615
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF3
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121646585A
Compound location

COMPARATIVE COMPOUND B

COMPARATIVE COMPOUND B enlarged structureCOMPARATIVE COMPOUND B location on patent page 72
Activity table
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