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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A019445

Assay: % DegradationTarget: GSPT1QC: standardized

Activity overview

Dmax = 61 %

TargetGSPT1

Cell line293A

ConcentrationConcentration series: 5000 nM, 1000 nM, 200 nM, 40 nM, 8 nM, 1.6 nM, 0.32 nM, 0.064 nM, 0.0128 nM, 0 nM

Time6 h

Assay / Readoutluminescence / Dmax

Assay IDPGDB_AS000716

PatentCN121591645A

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C001070

Compound1;1;化合物1

Source record IDPGDB_C001070

InChIKeyDPKDVLWRMCCJSA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000716

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

Technologyluminescence

ConcentrationConcentration series: 5000 nM, 1000 nM, 200 nM, 40 nM, 8 nM, 1.6 nM, 0.32 nM, 0.064 nM, 0.0128 nM, 0 nM

Treatment time6 h

Detection targetprotein_degradation

TargetGSPT1

E3Not specified

Cell line293A

Source evidence

Patent IDCN121591645A

Compound location

1;1;化合物1

1;1;化合物1 enlarged structure

1;1;化合物1 location on patent page 3

Activity table

Page 21 · table single

A patent-derived molecular glue bioactivity database with traceable evidence.

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0 countries/regions

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SIMM · NJU