Activity record

PGDB_A019545

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 4.6 nM

TargetGSPT1
Cell lineHL-60
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002047
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005359
Compound IDPGDB_C005359
Compound5-17b;5-17b;5-17b
Source record IDPGDB_C005359
InChIKeyYIECVHXDDOHUTO-UNMCSNQZSA-N

Assay context

Assay IDPGDB_AS002047
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023078410A1
Compound location

5-17b;5-17b;5-17b

5-17b;5-17b;5-17b enlarged structure5-17b;5-17b;5-17b location on patent page 8
Activity table
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