Activity record

PGDB_A019709

Assay: biochemicalTarget: KRASQC: standardized
Activity overview

IC50 = 10-100 nM

TargetKRAS
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000307
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011591
Compound IDPGDB_C011591
CompoundExample 4
Source record IDPGDB_C011591
InChIKeyUPSZSXSCKVWDIL-OOQVZLBDSA-N

Assay context

Assay IDPGDB_AS000307
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetRAF1
E3Not specified

Source evidence

Patent IDWO2025214350A1
Compound location

Example 4

Example 4 enlarged structureExample 4 location on patent page 57
Activity table
Page 221 · table start
Page 222 · table end