Activity record

PGDB_A019882

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

potency_ratio = 0-1.3 fold

TargetGSPT1
Cell lineGP2D
Time72 h
ControlRef1
Assay / ReadoutCCK-8 / Fold change
Assay IDPGDB_AS001306
PatentWO2025026218A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005378
Compound IDPGDB_C005378
Compound化合物 C008
Source record IDPGDB_C005378
InChIKeyMJYWBJDFZOYALU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001306
Assay familyviability
Assay systemcell_based
ReadoutFold change
TechnologyCCK-8
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineGP2D
OrganismHomo sapiens

Source evidence

Patent IDWO2025026218A1
Compound location

化合物 C008

化合物 C008 enlarged structure化合物 C008 location on patent page 35
Activity table
Page 111 · table single