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Patent
WO2025026218A1
77 compounds155 activity records4 assays
Patent summary
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Potency ratio | Ref1 | = | 0-1.3 | fold | - | — | - | - | NCI-H1155 | PGDB_A007489 | PGDB_C005413 | PGDB_AS001532 | View |
 | % Inhibition | - | = | 37.69 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A007639 | PGDB_C005388 | PGDB_AS000603 | View |
 | Potency ratio | Ref1 | = | 1.3-2 | fold | - | — | - | - | MDA-MB-468 | PGDB_A008230 | PGDB_C005410 | PGDB_AS001889 | View |
| Potency ratio | Ref1 | = | 1.3-2 | fold | - | — | - | - | MDA-MB-468 | PGDB_A008669 | PGDB_C005413 | PGDB_AS001889 | View |
 | % Inhibition | - | = | 60.74 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A009294 | PGDB_C005427 | PGDB_AS000603 | View |
 | Potency ratio | Ref1 | = | 2-10 | fold | - | — | GSPT1 | - | GP2D | PGDB_A009539 | PGDB_C005374 | PGDB_AS001306 | View |
| % Inhibition | - | = | 11.7 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A009743 | PGDB_C005413 | PGDB_AS000603 | View |
 | Potency ratio | Ref1 | = | 0-1.3 | fold | - | — | - | - | NCI-H1155 | PGDB_A009750 | PGDB_C005411 | PGDB_AS001532 | View |
 | Potency ratio | Ref1 | = | 2-10 | fold | - | — | - | - | NCI-H1155 | PGDB_A010298 | PGDB_C005430 | PGDB_AS001532 | View |
 | % Inhibition | - | = | 52.8 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A010543 | PGDB_C005432 | PGDB_AS000603 | View |
 | % Inhibition | - | = | 60.94 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A011423 | PGDB_C005423 | PGDB_AS000603 | View |
 | Potency ratio | Ref1 | = | 2-10 | fold | - | — | - | - | MDA-MB-468 | PGDB_A011666 | PGDB_C005431 | PGDB_AS001889 | View |
 | % Inhibition | - | = | 16.23 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A011684 | PGDB_C005429 | PGDB_AS000603 | View |
 | Potency ratio | Ref1 | = | 2-10 | fold | - | — | - | - | MDA-MB-468 | PGDB_A012414 | PGDB_C005417 | PGDB_AS001889 | View |
 | Potency ratio | Ref1 | = | 2-10 | fold | - | — | - | - | MDA-MB-468 | PGDB_A013826 | PGDB_C005434 | PGDB_AS001889 | View |
 | % Inhibition | - | = | 20.59 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A014065 | PGDB_C005390 | PGDB_AS000603 | View |
 | Potency ratio | Ref1 | = | 2-10 | fold | - | — | - | - | NCI-H1155 | PGDB_A014926 | PGDB_C005442 | PGDB_AS001532 | View |
| % Inhibition | - | = | 48.92 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A015678 | PGDB_C005434 | PGDB_AS000603 | View |
 | Potency ratio | Ref1 | = | 0-1.3 | fold | - | — | - | - | MDA-MB-468 | PGDB_A015803 | PGDB_C005445 | PGDB_AS001889 | View |
| % Inhibition | - | = | 45.18 | % | Concentration series: 3 uM, 5 uM, 10 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A018419 | PGDB_C005410 | PGDB_AS000603 | View |