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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A020005

Assay: % DegradationTarget: CDK2QC: standardized

Activity overview

IC50 = 0.041 uM

TargetCDK2

Cell lineHEK293

Time6 h

Assay / Readoutluminescence / IC50

Assay IDPGDB_AS002100

PatentWO2025043225

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C008137

Compound226;226

Source record IDPGDB_C008137

InChIKeyMJNMAKILZDMWIG-MPYYAJLASA-N

Assay context

Assay IDPGDB_AS002100

Assay family% Degradation

Assay systemcell_based

ReadoutIC50

Technologyluminescence

Treatment time6 h

Detection targetprotein_degradation

TargetCDK2

E3Not specified

Cell lineHEK293

OrganismHomo sapiens

Source evidence

Patent IDWO2025043225

Compound location

226;226

226;226 enlarged structure

226;226 location on patent page 51

Activity table

Page 529 · table start

Page 530 · table middle

Page 531 · table middle

Page 532 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU