Activity record

PGDB_A020041

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki = 0.44 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS002388
PatentUS12110292B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009000
Compound IDPGDB_C009000
Compound14;14;14
Source record IDPGDB_C009000
InChIKeyHQIHAVBDCVQJOE-IKJXHCRLSA-N

Assay context

Assay IDPGDB_AS002388
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12110292B2
Compound location

14;14;14

14;14;14 enlarged structure14;14;14 location on patent page 28
Activity table
Page 102 · table start
Page 103 · table end