Activity record

PGDB_A020358

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

Dmax = 43 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000735
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008044
Compound IDPGDB_C008044
Compound63;63;63
Source record IDPGDB_C008044
InChIKeyBRYXRQRWINPDGL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000735
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

63;63;63

63;63;63 enlarged structure63;63;63 location on patent page 40
Activity table
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