Activity record

PGDB_A020429

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 > 30 uM

TargetGSPT1
Cell lineHEK293T
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001378
PatentCN117836288A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000464
Compound IDPGDB_C000464
Compound125;125
Source record IDPGDB_C000464
InChIKeyDQYZQRGRHXEYPT-GVAUOCQISA-N

Assay context

Assay IDPGDB_AS001378
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDCN117836288A
Compound location

125;125

125;125 enlarged structure125;125 location on patent page 60
Activity table
Page 163 · table single