Activity record

PGDB_A020533

Assay: biochemicalTarget: KRASQC: standardized
Activity overview

IC50 = 10-100 nM

TargetKRAS
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000928
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011590
Compound IDPGDB_C011590
CompoundExample 3
Source record IDPGDB_C011590
InChIKeyULGAFHWEFIIKOS-FSIGLRKVSA-N

Assay context

Assay IDPGDB_AS000928
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetRAF1 | SOS1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025214350A1
Compound location

Example 3

Example 3 enlarged structureExample 3 location on patent page 57
Activity table
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