Activity record

PGDB_A020639

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 < 100 nM

TargetGSPT1
Cell lineHEK293
Time6 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002200
PatentWO2023237116A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002213
Compound IDPGDB_C002213
CompoundExample 48
Source record IDPGDB_C002213
InChIKeyPHLKUXIZZPURJP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002200
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2023237116A1
Compound location

Example 48

Example 48 enlarged structureExample 48 location on patent page 201
Activity table
Page 387 · table single