PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2023237116A1

AssigneeZhuhai Woo Biological Science And Technology

TitleProtein degradation agents and uses thereof

Family ID89117589

Family members4

Filing year2023

Publication date2025-03-14

JurisdictionWO

Compounds114

Activity records229

Assays7

Activity compounds and values

Activity records

229 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
GI50	-	<	100	nM	-	—	GSPT1	-	HL-60	PGDB_A008007	PGDB_C002250	PGDB_AS001555	View
GI50	-	=	22.29	nM	-	—	GSPT1	-	Hep3B	PGDB_A009004	PGDB_C002259	PGDB_AS001914	View
DC50	-	<	100	nM	-	—	GSPT1	-	HEK293	PGDB_A009125	PGDB_C002253	PGDB_AS002200	View
DC50	-	<	100	nM	-	—	GSPT1	-	HEK293	PGDB_A009352	PGDB_C002274	PGDB_AS002200	View
DC50	-	<	100	nM	-	—	GSPT1	-	HEK293	PGDB_A009563	PGDB_C002266	PGDB_AS002200	View
DC50	-	<	100	nM	-	—	GSPT1	-	HEK293	PGDB_A010038	PGDB_C002214	PGDB_AS002200	View
DC50	-	<	100	nM	-	—	GSPT1	-	HEK293	PGDB_A010570	PGDB_C002237	PGDB_AS002200	View
DC50	-	<	100	nM	-	—	GSPT1	-	HEK293	PGDB_A010862	PGDB_C002206	PGDB_AS002200	View
GI50	-	=	100-1000	nM	-	—	GSPT1	-	HL-60	PGDB_A011190	PGDB_C002248	PGDB_AS001555	View
GI50	-	<	100	nM	-	—	GSPT1	-	HL-60	PGDB_A011499	PGDB_C002298	PGDB_AS001555	View
DC50	-	<	100	nM	-	—	GSPT1	-	HEK293	PGDB_A011994	PGDB_C002260	PGDB_AS002200	View
GI50	-	<	100	nM	-	—	GSPT1	-	HL-60	PGDB_A012098	PGDB_C002256	PGDB_AS001555	View
DC50	-	=	100-1000	nM	-	—	GSPT1	-	HEK293	PGDB_A012610	PGDB_C002245	PGDB_AS002200	View
GI50	-	<	100	nM	-	—	GSPT1	-	HL-60	PGDB_A013305	PGDB_C002237	PGDB_AS001555	View
GI50	-	=	11.38	nM	-	—	GSPT1	-	SU-DHL-2	PGDB_A013438	PGDB_C002218	PGDB_AS000205	View
GI50	-	=	100-1000	nM	-	—	GSPT1	-	HL-60	PGDB_A014058	PGDB_C002312	PGDB_AS001555	View
GI50	-	=	1000-5000	nM	-	—	GSPT1	-	HL-60	PGDB_A014228	PGDB_C002294	PGDB_AS001555	View
GI50	-	=	19.61	nM	-	—	GSPT1	-	Toledo	PGDB_A014474	PGDB_C002208	PGDB_AS002036	View
GI50	-	=	0.96	nM	-	—	GSPT1	-	Toledo	PGDB_A014475	PGDB_C002229	PGDB_AS002036	View
DC50	-	<	100	nM	-	—	GSPT1	-	HEK293	PGDB_A014996	PGDB_C002220	PGDB_AS002200	View

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