Activity record

PGDB_A020703

Assay: % DegradationQC: standardized
Activity overview

EC50 > 30 uM

Cell line293GT
Time14 h
Assay / Readoutluminescence / EC50
Assay IDPGDB_AS002316
PatentCN111051298A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C022723
Compound IDPGDB_C022723
CompoundI-125
Source record IDPGDB_C022723
InChIKeyJGFPJYXRZZILFZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002316
Assay family% Degradation
Assay systemcell_based
ReadoutEC50
Technologyluminescence
Treatment time14 h
Detection targetprotein_degradation
TargetGSPT1
E3CRBN
Cell line293GT
OrganismHomo sapiens

Source evidence

Patent IDCN111051298A
Compound location

I-125

multi-compoundsneed check
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