PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN111051298A

AssigneeNovartis

Family members63

Filing year2,018

JurisdictionCN

Compounds151

Activity records507

Assays8

Activity compounds and values

Activity records

507 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
% Degradation	-	=	55.0	%	10 uM	24 h	-	-	293GT	PGDB_A007048	PGDB_C022664	PGDB_AS002112	View
% Degradation	-	=	60.0	%	10 uM	24 h	-	-	293GT	PGDB_A007230	PGDB_C022669	PGDB_AS002112	View
EC50	-	>	30.0	uM	-	—	-	-	293GT	PGDB_A007300	PGDB_C022706	PGDB_AS000334	View
EC50	-	>	30.0	uM	-	—	-	-	293GT	PGDB_A007341	PGDB_C022693	PGDB_AS002316	View
EC50	-	=	1.08	uM	-	—	-	-	293GT	PGDB_A007428	PGDB_C022729	PGDB_AS001169	View
% Degradation	-	=	60.0	%	10 uM	24 h	-	-	293GT	PGDB_A007471	PGDB_C022735	PGDB_AS002112	View
EC50	-	>	30.0	uM	-	—	-	-	293GT	PGDB_A007513	PGDB_C022690	PGDB_AS000334	View
% Degradation	-	=	50.0	%	10 uM	24 h	-	-	293GT	PGDB_A007536	PGDB_C022645	PGDB_AS002112	View
% Degradation	-	=	70.0	%	10 uM	24 h	-	-	293GT	PGDB_A007588	PGDB_C022694	PGDB_AS002112	View
% Degradation	-	=	50.0	%	10 uM	24 h	-	-	293GT	PGDB_A007938	PGDB_C022742	PGDB_AS002112	View
EC50	-	>	30.0	uM	-	—	-	-	293GT	PGDB_A007950	PGDB_C022654	PGDB_AS002316	View
EC50	-	=	0.031	uM	-	—	-	-	293GT	PGDB_A008080	PGDB_C022761	PGDB_AS001169	View
% Degradation	-	=	80.0	%	10 uM	24 h	-	-	293GT	PGDB_A008190	PGDB_C022746	PGDB_AS002112	View
EC50	-	>	30.0	uM	-	—	-	-	293GT	PGDB_A008258	PGDB_C022766	PGDB_AS000334	View
% Degradation	-	=	5.0	%	10 uM	24 h	-	-	293GT	PGDB_A008579	PGDB_C022702	PGDB_AS002112	View
EC50	-	=	0.11	uM	-	—	-	-	293GT	PGDB_A008607	PGDB_C022714	PGDB_AS001169	View
% Degradation	-	=	50.0	%	10 uM	24 h	-	-	293GT	PGDB_A008617	PGDB_C022649	PGDB_AS002112	View
% Degradation	-	=	70.0	%	10 uM	24 h	-	-	293GT	PGDB_A008804	PGDB_C022732	PGDB_AS002112	View
% Degradation	-	=	50.0	%	10 uM	24 h	-	-	293GT	PGDB_A008875	PGDB_C022681	PGDB_AS002112	View
EC50	-	=	0.17	uM	-	—	-	-	293GT	PGDB_A008963	PGDB_C022735	PGDB_AS001169	View

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