Activity record

PGDB_A020741

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 9.23 nM

TargetGSPT1
Cell lineNCI-H1155
Time3 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS001039
PatentCN118852145A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001455
Compound IDPGDB_C001455
Compound实施例3
Source record IDPGDB_C001455
InChIKeyKJXVGCUSLDVTFU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001039
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time3 d
TargetGSPT1
E3Not specified
Cell lineNCI-H1155
OrganismHomo sapiens

Source evidence

Patent IDCN118852145A
Compound location

实施例3

实施例3 enlarged structure实施例3 location on patent page 26
Activity table
Page 89 · table start
Page 90 · table end