Activity record

PGDB_A020749

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 70-80 %

TargetCRBN
E3 ligaseCRBN
Concentration2 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS001462
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000856
Compound IDPGDB_C000856
CompoundGT-09688
Source record IDPGDB_C000856
InChIKeyIAUXPEVRTOYJDH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001462
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration2 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN

Source evidence

Patent IDCN120548310A
Compound location

GT-09688

GT-09688 enlarged structureGT-09688 location on patent page 45
Activity table
Page 147 · table start
Page 148 · table end