Activity record

PGDB_A020786

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

Dmax = 14 %

TargetIKZF3
Cell lineJurkat
Time24 h
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS002580
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007381
Compound IDPGDB_C007381
CompoundComparative Compound A
Source record IDPGDB_C007381
InChIKeyOHSPSWUQMQUVMW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002580
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Treatment time24 h
TargetIKZF3
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

Comparative Compound A

Comparative Compound A enlarged structureComparative Compound A location on patent page 86
Activity table
Page 87 · table single