Activity record

PGDB_A021078

Assay: viabilityTarget: CDK12QC: ambiguous
Activity overview

IC50 = 4.3 nM

TargetCDK12
Cell lineA673
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS002570
PatentCN114929708B
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006577
Compound IDPGDB_C006577
CompoundH-APPAMP-010
Source record IDPGDB_C006577
InChIKeyZFPYLHAKPYYSGF-XLIONFOSSA-N

Assay context

Assay IDPGDB_AS002570
Assay familyviability
Assay systemcell_based
ReadoutIC50
TargetCDK12
E3Not specified
Cell lineA673

Source evidence

Patent IDCN114929708B
Compound location

H-APPAMP-010

H-APPAMP-010 enlarged structureH-APPAMP-010 location on patent page 38
Activity table
Page 198 · table start
Page 199 · table end