Activity record

PGDB_A021302

Assay: % DegradationTarget: IKZF2QC: standardized
Activity overview

DC50 = 2.2 nM

TargetIKZF2
Time13 d
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001453
PatentCN121646585A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007381
Compound IDPGDB_C007381
CompoundCOMPARATIVE COMPOUND A
Source record IDPGDB_C007381
InChIKeyOHSPSWUQMQUVMW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001453
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time13 d
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121646585A
Compound location

COMPARATIVE COMPOUND A

COMPARATIVE COMPOUND A enlarged structureCOMPARATIVE COMPOUND A location on patent page 71
Activity table
Page 78 · table single