Activity record

PGDB_A021393

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 2.1 nM

TargetGSPT1
Cell lineMOLM-13
TimeThree days later
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001125
PatentWO2022073469A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004676
Compound IDPGDB_C004676
CompoundGS-004
Source record IDPGDB_C004676
InChIKeyVSDUDXRVTVAKOG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001125
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment timeThree days later
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineMOLM-13

Source evidence

Patent IDWO2022073469A1
Compound location

GS-004

GS-004 enlarged structureGS-004 location on patent page 76
Activity table
Page 482 · table single